TOPICS expected to be covered during the IRT 2020
Synthesis, modifications, methods, prebiotic chemistry
OLIGONUCLEOTIDE DESIGN AND CHEMISTRY
Synthesis, modifications, conjugates, labeling, capping, ON and guide RNA design
Prodrugs, antiviral and antibacterial nucleosides
OLIGONUCLEOTIDE/RNA BASED THERAPY
siRNA, mRNA, microRNA and antisense therapy, miRNA targeting, splice correction/switching, gene activation/editing and toxicity.
DELIVERY AND TARGETING OF NUCLEOSIDES AND OLIGONUCLEOTIDES
Cellular uptake-enhancing and tissue-targeting modifications and conjugates, intracellular trafficking, protein interaction.
APPLICATIONS OF NUCLEIC ACIDS BEYOND THERAPY
Nanotechnology, origami, diagnostics, biophysics of nucleic acids, mechanisms and reactions involving nucleic acid components
NUCLEIC ACIDS: STRUCTURE, RECOGNITION AND CLEAVAGE
Aptamers, ribozymes/DNAzymes, artificial nucleases, enzymology of nucleic acid processing, small molecule recognition of nucleic acids, CRISPR/Cas